Amiodarone
Amiodarone is an investigational antiarrhythmic agent initially introduced as an antianginal coronary vasodilator. It has a broad spectrum of antiarrhythmic efficacy against supra ventricular and ventricular arrhythmias. Even though it prolongs the QT interval, it may suppress arrhythmias in patients with the long QT syndrome. It is effective in AV nodal reentry, reciprocating tachycardias associated with the Wolff-Parkinson-White syndrome, atrial flutter, and atrial fibrillation, as well as ventricular tachyarrhythmias. Antiarrhythmic efficacy develops after several days of oral administration but may occur earlier With intravenous administration. Amiodarone prolongs action potential duration and refractdriness in all cardiac tissues, slows sinus discharge, and prolongs AV nodal conduction time. Because of a variety of adverse effects, amiodarone should be administered to patients with highly symptomatic or life-threatening arrhythmias and orily if conventional drug therapy has failed.
- RESPIRATORY CONTROL CENTERS
- VENTRICULAR RHYTHM DISTURBANCES
- GROSS ANATOMY
- EMBOLIC DISEASE
- VARIATiT ANGINA
- EFFECTORS OF THE RESPIRATORY SYSTEM
- Anatomical Imaging of the Urinary
- APPROACH TO THE PATIENT WITH RENAL DISEASE
- Hypersensitivity Pneumonitis
- RENAL PHARMACOLOGY
- OTHER ESOPHAGEAL DISORDERS
- Hepatic Diseases
- Treatment and Prognosis
- ARTERIOSCLEROSIS OBLITERANS
- Renal Biopsy
- Disopyramide
- DEFINITION
- Idiopathic Pulmonary Fibrosis
- DRUGS
- CLINICAL MANIFESTATIONS OF ENDSTAGE RENAL DISEASE
- THE COMMON CLINICAL MANIFESTATIONS OF GASTROINTESTINAL DISEASE
- CHEST WALL DISEASE
- Other Glomerulonephritides
- Minimal Change Nephropathy
- Blood Chemistries
- Systemic Lupus Erythematosus (SLE)
- TREATMENT
- Upper GI Bleeding
- CHIP Perinatal Coverage
- Renal Venous Occlusion
- MECHANISMS OF ARRHYTHMOGENESIS
- Bleeding Diatheses
- OTHER THERAPEUTIC MODALITIES
- Gardner's Syndrome
- SPECIFIC ARRHYTHMIAS - sinus nodal rhythm disturbances