FACTORS AFFECTING THE RATE OF LOSS OF NEPHRONS
It has been appreciated for some time that many patients have a slow, steady decline in renal function over a period of months to years . A number of pathogenetic mechanisms have been implicated in the slow decline in renal function.
Continuing Primary Insult. It is often suggested that the disease initially causing the renal injury is still active and results in progressive damage. Frequently, despite the progressive loss of renal function, it is not possible to identify continued activity of the primary disease or exposure to toxins.
Secondary Renal Insults. In some circumstances, there may be development of secondary insults to the kidney, and these secondary processes could account for the progression of renal insufficiency. Congestive heart failure, hypercalcemia, infection, obstruction to urine flow, exposure to nephrotoxic drugs, or alterations in the extracellular fluid volume may result in further decreases in renal function.
- Urinary Tract Obstruction
- BRORICHODILATORS
- RENAL PHARMACOLOGY
- Lower GI Bleeding
- Amiodarone
- CARCINOMA OF THE COLON
- Plain Radiographs and Barium Contrast Studies
- AORTIC DISEASE - AORTIC ANEURYSMS
- LABORATORY TESTS IN LIVER DISEASE
- EMPHYSEMA
- Women’s Health Program
- Clinical Manifestations
- BROliCHIECTASIS
- Bleeding Diatheses
- Nephrosclerosis
- OBLITERATIVE OR OBSTRUCTIVE PULMONARY HYPERTENSION
- New Eligibility System
- Determination of Kidney Anatomy and Renal Blood Flow
- Hematopoietic System
- NAUSEA AND VOMITING
- MEDIASTINITIS
- NORMAL ESOPHAGEAL PHYSIOLOGY
- VENTILATION
- Membranoproliferative Glomerulonephritis (MPGN)
- Clinical Manifestations
- Treatment and Prognosis
- CONSTRICTIVE PERICARDITIS
- TREATMENT
- Renal Venous Occlusion
- ANTIBIOTICS
- RHEUMATIC FEVER
- Direct (Toxic Nephropathy)
- Improving Case Management
- GASTROESOPHAGEAL REFLUX DISEASE
- PRINCIPLES OF CARDIOPULMONARY RESUSCITATION